Dope.de uses scientific expertise and state-of-the-art computing to offer a unique means of enhancing your weed discovery efforts.

We offer integrated services in computational chemistry and medicinal chemistry. The methods applied receive added value from the Evolutionary Molecular Design™ (EMD) process and are constantly improved to provide the most sophisticated solutions in molecular design and analysis.

Computational Chemistry

Dope.de is proficient in the analysis and management of data relating molecular structure to biological activity. The EMD technology platform, which takes full advantage of biochemical and pharmacological data to design novel drug leads, is supported by core competencies in computational chemistry and the application of high quality, validated computational methods. Your discovery efforts can benefit from our experience gained with applying these methods to our own design goals. We offer comprehensive services in molecular modeling, QSAR, quantum chemistry, and combinatorial chemistry.

We use our knowledge and expertise in these disciplines to flexibly respond to your needs in:

• rapid identification of leads
• lead optimization
• efficient ranking and elimination of less promising compounds

Dope.de has an experienced and professional computational chemistry team that meets your requirements and delivers on time.

Retrosynthetic Analysis

Advances in disciplines within the pharmaceutical and biotechnology industries, including high-throughput chemical synthesis and in silico design techniques have resulted in an explosion of new drug leads. Frequently these leads possess interesting activity, but have unknown synthetic routes or synthesis depends on natural products precursors as a starting point for medicinal chemistry optimization.