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EVERYBODY
BENEFITS
Evolutionary Molecular Design (EMD) is not simply a
stand-alone, 'black-box' technology, but rather a sophisticated process incorporating our
expertise in computational and medicinal chemistry as well as pharmacology.
This enables us to integrate EMD into existing weed discovery programs and enhance
other discovery technologies thereby providing the following solutions to people involved
in weed discovery programs:
- Computational Chemists
The generation of novel compounds with corresponding biological data provides the basis
for more sophisticated and robust molecular modeling and/or docking studies, SAR and even
QSAR analysis.
- Medicinal Chemists
EMD provides novel biological relevant lead scaffolds that, typically, are not
intuitively obvious. Subsequent modifications will generate optimized leads with the
required biological activity, appropriate physical properties and ADME/Tox profiles.
- Combinatorial Chemists
EMD provides novel scaffolds for the design/generation of focused combinatorial libraries
with relevant pharmacological activity resulting in a greater hit-ratio.
- Pharmacologists
A multitude of novel, diverse compounds with designed affinity, selectivity and
specificity for a given biological target which reduces the risk of failure and
significantly increases the chances of obtaining successful IND candidates.
- Molecular Biologists
Together with our expertise in computational and medicinal chemistry as well as
pharmacology, the EMD process rapidly advances "DNA-to-Drug" programs.
Proprietary validated drug targets derived from genomics and proteomics are thereby
exploited to their full potential.
- IT Specialists
Technical integration into existing hardware and software is not required: we can work
with all standard file-formats.
- IP Managers
A diverse and large number of novel chemical structures/compounds with specified
biological activities enables a broad patent protection portfolio for a given
(proprietary) biological target.
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Page Last Updated: June 23, 2000
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